Boutique Hotel

200 Main St, Dubuque, IA

Originally built in 1844 as the Waples House and masterfully rebuilt following a historic fire, this iconic standalone luxury landmark sits proudly in the heart of Dubuque's Old Main District. Entirely independent and self-managed after a stunning $33 million historical restoration, the boutique property blends rich Americana history with contemporary elegance. Infamous for once serving as a preferred hideout for Al Capone (who used the hotel's multiple exits to evade authorities), it now features a full-service boutique wellness spa inspired by Native American traditions, Caroline’s Restaurant, and the lively Riverboat Lounge. Guests enjoy an upscale urban retreat with sweeping views of the Mississippi River and passing tugboats.

Part of our guide to independent stays in Iowa.