Boutique Hotel

603 N Henderson Ave, Cape Girardeau, MO

Experience a sophisticated stay at this stunning boutique hotel tucked inside Cape Girardeau’s historic downtown Boulevard District. Featuring seven exquisitely designed guest rooms, the inn seamlessly blends nostalgic architecture with contemporary luxuries like plush robes, a grand Steinway piano lobby, and an EV charging station. Guests can sip morning coffee on a private garden patio or unwind in a stylish, speakeasy-inspired evening lounge.

Part of our guide to independent stays in Missouri.